The impact of COVID-19 virus and vaccination on the pregnancy and breastfeeding women in Makkah region


  • Suad AlJabari Faculty of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia.
  • Rawan Almatrafi Faculty of Pharmacy, Umm Al-Qura University, Makkah, Saudi Arabia.
  • Yosra Alhindi Associate professor, Department Pharmacology and Toxicology, College of Medicine Umm Al-Qura University, Makkah, Saudi Arabia


Pregnant women, Breastfeeding, Covid-19 infection, Vaccine, Perception


Background: Pregnant women usually have a lower acceptance rate and more concerns about vaccination than the general population. There aren't sufficient prior studies on the effect of COVID-19 vaccination on Saudi Arabian pregnant and breastfeeding women either on pregnancy outcomes or on the fetus status. Therefore, the purpose of this study is to identify the impact of the COVID-19 virus and vaccination on pregnancy, pregnancy outcomes, and fetus during the lactation period in women living in Makkah region, Saudi Arabia; in addition, it aims to assess the knowledge, perception, and attitude of pregnant women toward COVID-19 vaccine.

Methods: A cross-sectional study was conducted in four major hospitals in Makkah, Saudi Arabia, between January and October 2023. Data was collected through a valid questionnaire, The study included women aged 18-55, who provided informed consent and received the vaccine. Quantitative data analysis was performed using Excel software.

Results: The study involved 543 women, mainly younger than 50, with 50.1% expecting or breastfeeding, almost 25% had a history of COVID-19 infection and 55% had received immunization, The study reveals that 66.2% of women have received other vaccine brands in the past three years, with 90.1% believing they have sufficient information about the COVID-19 vaccine. However, 55.6%), lack knowledge about vaccine safety during pregnancy and breastfeeding, and 34.5% believe it causes complications. Overall, 46.0% received at least two doses.

Conclusion: The study found that hesitancy to COVID-19 vaccination was primarily due to concerns about vaccine safety among 543 women who met inclusion criteria.


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How to Cite

AlJabari, S. ., Almatrafi, R. ., & Alhindi, Y. (2024). The impact of COVID-19 virus and vaccination on the pregnancy and breastfeeding women in Makkah region. Journal of Health Informatics in Developing Countries, 18(01). Retrieved from



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